Journal Of
Polyphenols

Abstract: Abstract In recent years, the incidence of liver diseases and diabetes is increasing year by year, and the patients are younger than before. Although the clinical medicine treatment is effective, but it would produce side eff ects. Radix Puerariae is the dried root of the Pueraria lobata (Willd.) Ohwi. Puerarin is an isofl avone compound with polyphenol structure. It is one of the main bioactive components of Radix Puerariae. Studies have found that the application of puerarin offers beatifical act on liver protection, hypoglycemia, blood lipid, antioxidant, anti-osteoporosis, anti-cancer, anti-inflammatory and cardiovascular protection. Puerarin has been used in the treatment of liver disease and diabetes. In this study, the effect of puerarin on liver protection, diabetes treatment and the relationship between the two diseases were reviewed. The therapeutic mechanism and molecular targets of puerarin were explored in order to further improve the development of puerarin and increase its clinical application in protection against liver disease and diabetes.

Key words: puerarin, liver protection, diabetes